CV Huber, Tobias B., Prof. Dr.
1) General Information
Name: HUBER, Tobias B., Prof. Dr.
Date of Birth: 25.08.1971
Gender: male
Address: Department of Medicine, Renal Division, University Medical Center Freiburg, Hugstetterstr. 55, 79106 Germany
Telephone/Fax: +49 (0) 761 270 35590, - 32700
Email: tobias.huber@uniklinik-freiburg.de
Position: W3-Heisenbergprofessor, Permanent attending position
Children: 2
2) Academic Education
10/1992 – 05/1999: School of Medicine (10/1992 – 05/1999), Universities of Freiburg, Vienna and South Florida (Tampa, USA)
3) Advanced Professional Degrees
Since 2013 W3-Heisenbergprofessorship for Chronic Kidney Disease and Ageing
2010: Professor (APL) for Internal Medicine, University Medical Center Freiburg; German Board Certification for Nephrology
2008: German Board Certification for Internal Medicine
2007: Habilitation, Experimental Medicine, Albert-Ludwigs-University Freiburg, advisor: Prof. Dr. Gerd Walz
2005: USMLE US-American Full Medical Licence
1999: MD in Physiology (summa cum laude), Department of Physiology, Albert-Ludwigs-University Freiburg, advisor: Prof. Dr. R Greger
4) Positions held
since 04/2017: Director and Chair of the III Medical Department, University Medical Center Hamburg-Eppendorf
2015 - 2017: Vice chair of the Department of Medicine IV, University Medical Center Freiburg
2015 - 2017: Chief of the Division of Chronic Kidney Disease, University Medical Center Freiburg
since 2015: Senior Fellow of the Freiburg Institute for Advanced Studies (FRIAS)
2015 - 2017: Co-Director of the Center of Systems Biology (ZBSA)
since 11/2013: W3-Heisenbergprofessorship
08/2011: Heisenberg Fellow
since 08/2011: Senior Attending Physician (Geschäftsführender Oberarzt)
since 05/2011: Coordinator of NephAge-BMBF Systemsbiology Consortium of Aging-
2010: Associate Professor of Medicine (APL-Professor)
12/2008 -2017: Attending Physician, Department of Medicine IV, University Medical Center Freiburg, Germany
2008: German Board Certification for Internal Medicine
2007: Assistant Professor, Habilitation (Venia legendi), University Freiburg
06/2006 – 07/2011: Emmy Noether Group leader, Department of Medicine IV, University Medical Center Freiburg, Germany
10/2003 – 05/2006: Postdoctoral Emmy Noether Fellow (Phase I), Immunology & Pathology, Washington University St. Louis, USA, Prof. Dr. A. Shaw
03/2001 – 09/2003: Fellow in Medicine, Department of Medicine IV, University Medical Center Freiburg, Germany
07/1999 – 02/2001: Residency, Department of Medicine IV, University Medical Center Freiburg, Germany
1995 – 1996: MD Thesis with Prof. Dr. Greger Institute of Physiology, University Freiburg
5) Other scientific activities
2014: Elected member of the American Society of Clinical Investigation
2014: Recipient of the European Research Council Grant
2012: Young Investigator Award of the American Society of Nephrology and the American Heart Association
2010: Invitation (Ruf) as Full Professor, Dept. of Nephrology, UT South Western Dallas; declined
2010: Invitation (Ruf) as Full Professor (W3), Dep. of Nephrology, University of Münster; declined
2010: Franz-Volhard Award of the German Renal Society
since 2010: Member of the German Society of Internal Medicine
2009: Hans U. Zollinger Research Award of German Renal Society
since 2008: Associated Member of the BIOSS Excellence Cluster, Freiburg
since 2007: Member of the German and American Renal Society
since 2006: PI of the SGBM Graduate School, Freiburg
2004: Carl Ludwig Award of the German Renal Society
2002: Young Nephrologist Award of the German Renal Society
1999: M.D., University of Freiburg, Germany (summa cum laude)
6) Most significant publications
a) Peer reviewed Publications
1. Godel M, Grahammer F, Huber TB. (2015). Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy. N Engl J Med 372(11):1073.10.1056/NEJMc1500130#SA1
2. Zhou Q, Neubauer J, Kern JS, Grotz W, Walz G, Huber TB. (2014). Calciphylaxis. Lancet 383(9922):1067.10.1016/S0140-6736(14)60235-X
3. Grahammer F, Haenisch N, Steinhardt F, Sander L, Roerden M, Arnold F, Cordts T, Wanner N, Reichardt W, Kerjaschki D, Ruegg MA, Hall MN, Moulin P, Busch H, Boerries M, Walz G, Artunc F, Huber TB. (2014). mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress. Proc Natl Acad Sci U S A 10.1073/pnas.1402352111
4. Canaud G, Bienaime F, Viau A, Treins C, Baron W, Nguyen C, Burtin M, Berissi S, Giannakakis K, Muda AO, Zschiedrich S, Huber TB, Friedlander G, Legendre C, Pontoglio M, Pende M, Terzi F. (2013). AKT2 is essential to maintain podocyte viability and function during chronic kidney disease. Nat Med 19(10):1288-96.10.1038/nm.3313
5. Zhou W, Otto EA, Cluckey A, Airik R, Hurd TW, Chaki M, Diaz K, Lach FP, Bennett GR, Gee HY, Ghosh AK, Natarajan S, Thongthip S, Veturi U, Allen SJ, Janssen S, Ramaswami G, Dixon J, Burkhalter F, Spoendlin M, Moch H, Mihatsch MJ, Verine J, Reade R, Soliman H, Godin M, Kiss D, Monga G, Mazzucco G, Amann K, Artunc F, Newland RC, Wiech T, Zschiedrich S, Huber TB, Friedl A, Slaats GG, Joles JA, Goldschmeding R, Washburn J, Giles RH, Levy S, Smogorzewska A, Hildebrandt F. (2012). FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair. Nat Genet 44(8):910-5.10.1038/ng.2347
6. Liu S, Hartleben B, Kretz O, Wiech T, Igarashi P, Mizushima N, Walz G, Huber TB. (2012). Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury. Autophagy 8(5):826-37.10.4161/auto.19419
7. Godel M, Hartleben B, Herbach N, Liu S, Zschiedrich S, Lu S, Debreczeni-Mor A, Lindenmeyer MT, Rastaldi MP, Hartleben G, Wiech T, Fornoni A, Nelson RG, Kretzler M, Wanke R, Pavenstadt H, Kerjaschki D, Cohen CD, Hall MN, Ruegg MA, Inoki K, Walz G, Huber TB. (2011). Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J Clin Invest 121(6):2197-209.10.1172/JCI44774
8. Hartleben B, Godel M, Meyer-Schwesinger C, Liu S, Ulrich T, Kobler S, Wiech T, Grahammer F, Arnold SJ, Lindenmeyer MT, Cohen CD, Pavenstadt H, Kerjaschki D, Mizushima N, Shaw AS, Walz G, Huber TB. (2010). Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J Clin Invest 120(4):1084-96.10.1172/JCI39492
9. Huber TB, Kwoh C, Wu H, Asanuma K, Godel M, Hartleben B, Blumer KJ, Miner JH, Mundel P, Shaw AS. (2006). Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin. J Clin Invest 116(5):1337-45.10.1172/JCI27400
10. *Huber TB, *Schermer B, Muller RU, Hohne M, Bartram M, Calixto A, Hagmann H, Reinhardt C, Koos F, Kunzelmann K, Shirokova E, Krautwurst D, Harteneck C, Simons M, Pavenstadt H, Kerjaschki D, Thiele C, Walz G, Chalfie M, Benzing T. (2006). Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels. Proc Natl Acad Sci U S A 103(46):17079-86.*equal contribution. 10.1073/pnas.0607465103